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BDBM239638 US9394309, 91

SMILES: Cc1ccc(cc1C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1)S(F)(F)(F)(F)F

InChI Key: InChIKey=QVONWCWLAUGNMF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239638   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor TIE-2


(Homo sapiens (Human))
BDBM239638
PNG
(US9394309, 91)
Show SMILES Cc1ccc(cc1C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1)S(F)(F)(F)(F)F
Show InChI InChI=1S/C25H20F5N5OS/c1-16-6-8-20(37(26,27,28,29)30)13-21(16)25(36)32-19-7-5-17(2)23(12-19)34-10-11-35-24(34)14-22(33-35)18-4-3-9-31-15-18/h3-15H,1-2H3,(H,32,36)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 215n/an/an/an/a7.022



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...


US Patent US9394309 (2016)


BindingDB Entry DOI: 10.7270/Q2C53JRC
More data for this
Ligand-Target Pair