BDBM24138 4-(3-hydroxyphenyl)-7-methoxy-N,N-dimethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide::tetrahydroisoquinoline (THIQ), 42

SMILES COc1ccc2C(CN(Cc2c1)C(=O)N(C)C)c1cccc(O)c1

InChI Key InChIKey=JTDVZPOLRBKDIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24138   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24138(4-(3-hydroxyphenyl)-7-methoxy-N,N-dimethyl-1,2,3,4...)
Affinity DataIC50:  617nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed