BDBM24148 10-(3-hydroxyphenyl)-N,N-dimethyl-3-oxa-12-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),7-triene-12-carboxamide::tetrahydroisoquinoline (THIQ), 52

SMILES CN(C)C(=O)N1CC(c2cccc(O)c2)c2ccc3CCOc3c2C1

InChI Key InChIKey=UCOIZFMGCXDQLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24148   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24148(10-(3-hydroxyphenyl)-N,N-dimethyl-3-oxa-12-azatric...)
Affinity DataIC50:  639nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed