BDBM244056 US9428478, TG6-149

SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)CNc1ccc(cc1)C(C)C

InChI Key InChIKey=DVHHONQUMAGFHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244056   

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM244056(US9428478, TG6-149)
Affinity DataIC50: >2.00E+10nMAssay Description:Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM244056(US9428478, TG6-149)
Affinity DataIC50:  8.00E+8nMAssay Description:Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent