BDBM244099 2-(((1r,4s)-4-cyanocyclohexyl)amino)-n-((s)-2-hydroxy-1-phenylethyl)-5,5-dimethyl-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide::US9546173, cmpd 81

SMILES CC1(C)N(Cc2nc(N[C@H]3CC[C@@H](CC3)C#N)ncc12)C(=O)N[C@H](CO)c1ccccc1

InChI Key InChIKey=SELOVRYKWRDXGP-HGHGUNKESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244099   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244099(2-(((1r,4s)-4-cyanocyclohexyl)amino)-n-((s)-2-hydr...)
Affinity DataIC50:  114nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent