BDBM24413 JMC521864 Compund DSM2::N-(anthracen-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::Triazolopyrimidine-Based Compound, 20

SMILES Cc1cc(Nc2ccc3cc4ccccc4cc3c2)n2ncnc2n1

InChI Key InChIKey=OXYDLVAOXASTMW-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24413   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Texas At Dallas

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50:  56nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University Of Washington At Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University Of Washington At Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50:  3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Texas At Dallas

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50:  56nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair