BDBM244171 US9546173, cmpd 103::n-(1-(3-chlorobenzyl)-5-(methylcarbamoyl)piperidin-3-yl)-5,5-dimethyl-2-((tetrahydro-2h-pyran-4-yl)amino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CNC(=O)C1CC(CN(Cc2cccc(Cl)c2)C1)NC(=O)N1Cc2nc(NC3CCOCC3)ncc2C1(C)C

InChI Key InChIKey=MTPOIINKMCMSED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244171   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244171(US9546173, cmpd 103 | n-(1-(3-chlorobenzyl)-5-(met...)
Affinity DataIC50:  9.19E+3nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent