BDBM244239 US9546173, cmpd 159::n-((1-benzylpyrrolidin-3-yl)methyl)-5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CC1(C)N(Cc2nc(Nc3ccccc3)ncc12)C(=O)NCC1CCN(Cc2ccccc2)C1

InChI Key InChIKey=OAFLSSJHAZZTEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244239   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244239(US9546173, cmpd 159 | n-((1-benzylpyrrolidin-3-yl)...)
Affinity DataIC50:  5.65E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244239(US9546173, cmpd 159 | n-((1-benzylpyrrolidin-3-yl)...)
Affinity DataIC50:  1.96E+4nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent