BDBM244250 US9546173, cmpd 170::n-((r)-1-(3-chlorophenyl)ethyl)-5-methyl-2-((tetrahydro-2h-pyran-4-yl)amino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide (72)

SMILES C[C@@H](NC(=O)N1Cc2nc(NC3CCOCC3)ncc2C1C)c1cccc(Cl)c1

InChI Key InChIKey=YHYNZEWNUFKTDU-KWCCSABGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244250   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244250(US9546173, cmpd 170 | n-((r)-1-(3-chlorophenyl)eth...)
Affinity DataIC50:  1.54nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent