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BDBM249359 US9464062, 3

SMILES: CC(C)N1CC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)OC1=O

InChI Key: InChIKey=OJVAFYQQGTZNGB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249359   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor (2b and 2c)


(Homo sapiens (human))
BDBM249359
PNG
(US9464062, 3)
Show SMILES CC(C)N1CC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)OC1=O
Show InChI InChI=1S/C24H31N3O2/c1-19(2)27-18-22(29-24(27)28)17-25-13-15-26(16-14-25)23(20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,19,22-23H,13-18H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 274n/an/an/an/a7.4n/a



TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...


US Patent US9464062 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60MZC
More data for this
Ligand-Target Pair