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BDBM249361 US9464062, 5

SMILES: O=C1OC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)CN1C1CCCC1

InChI Key: InChIKey=SLLRBAPSNJOVOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249361   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor (2b and 2c)


(Homo sapiens (human))
BDBM249361
PNG
(US9464062, 5)
Show SMILES O=C1OC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)CN1C1CCCC1
Show InChI InChI=1S/C26H33N3O2/c30-26-29(23-13-7-8-14-23)20-24(31-26)19-27-15-17-28(18-16-27)25(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-6,9-12,23-25H,7-8,13-20H2
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 41n/an/an/an/a7.4n/a



TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...


US Patent US9464062 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60MZC
More data for this
Ligand-Target Pair