BDBM25144 (2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N-(4-phenyl-1,3-thiazol-2-yl)nonanamide::CHEMBL217651::bis-amide inhibitor, 15
SMILES CN1CCCCC1C(=O)N[C@@H](CCCCCC(C)=O)C(=O)Nc1nc(cs1)-c1ccccc1
InChI Key InChIKey=MVGAXXKEFDOLGL-AIBWNMTMSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 25144
Affinity DataIC50: 55nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC8 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HDAC5 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC3 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of HDAC2 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair