BDBM25422 3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benzonitrile::Triclosan derivative, 23

SMILES Oc1cc(ccc1Oc1ccc(cc1Cl)C#N)-c1ccccn1

InChI Key InChIKey=CSJXWYZNRAVKKT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25422   

TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
International Centre For Science And High Technology

Curated by ChEMBL
LigandPNGBDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Plasmodium falciparum enoyl-acyl carrier protein reductaseMore data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50:  700nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair