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BDBM258780 US9499482, 186

SMILES: CS(=O)(=O)C1CN(CCOc2ccc(cc2OC(F)F)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1

InChI Key: InChIKey=ZHWQJQYMKDYXFK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258780   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258780
PNG
(US9499482, 186)
Show SMILES CS(=O)(=O)C1CN(CCOc2ccc(cc2OC(F)F)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1
Show InChI InChI=1S/C26H28F2N2O6S/c1-37(32,33)21-15-29(16-21)12-13-34-22-9-6-19(14-24(22)36-26(27)28)30-11-10-23(25(30)31)35-20-7-4-18(5-8-20)17-2-3-17/h4-10,14,17,21,26H,2-3,11-13,15-16H2,1H3
GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.20n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair