BDBM25905 2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole-5-sulfonamide::BMC173212 Compound 2a::indole sulfonamide, 8a

SMILES Cc1ccccc1-c1c([nH]c2ccc(cc12)S(N)(=O)=O)C(=O)NN

InChI Key InChIKey=PPSRAFWOBCBARB-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 25905   

TargetCarbonic anhydrase 14(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  9.30nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  11.6nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  64nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  76nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  78nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  79nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  80nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  107nM ΔG°:  -9.50kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  326nM ΔG°:  -8.84kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  775nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  894nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  906nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  7.38E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  9.10E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  7.80E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed