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BDBM259938 US9512121, 17

SMILES: Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(N5CCOCC5)c(OCC5CC5)c4c3)n2c1

InChI Key: InChIKey=ZTDAGIXGKPWBTF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259938   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM259938
PNG
(US9512121, 17)
Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(N5CCOCC5)c(OCC5CC5)c4c3)n2c1
Show InChI InChI=1S/C27H27N7O2S/c1-32-15-20(13-29-32)19-4-7-25-30-31-27(34(25)16-19)37-21-5-6-23-22(12-21)26(36-17-18-2-3-18)24(14-28-23)33-8-10-35-11-9-33/h4-7,12-16,18H,2-3,8-11,17H2,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 8.5n/an/an/an/an/a20



Jiangsu Hansoh Pharmaceutical Co., Ltd.

US Patent


Assay Description
Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...


US Patent US9512121 (2016)


BindingDB Entry DOI: 10.7270/Q2ST7NSV
More data for this
Ligand-Target Pair