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BDBM260832 US9540323, 18::US9540323, example 18

SMILES: CC1(C)CN(c2c1c(ccc2O)C(F)(F)F)c1ccccc1NC(=O)Nc1nc2ccc(F)cc2s1

InChI Key: InChIKey=JCGMAIRZGDSBKN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260832   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y1


(Homo sapiens (Human))
BDBM260832
PNG
(US9540323, 18 | US9540323, example 18)
Show SMILES CC1(C)CN(c2c1c(ccc2O)C(F)(F)F)c1ccccc1NC(=O)Nc1nc2ccc(F)cc2s1
Show InChI InChI=1S/C25H20F4N4O2S/c1-24(2)12-33(21-18(34)10-8-14(20(21)24)25(27,28)29)17-6-4-3-5-15(17)30-22(35)32-23-31-16-9-7-13(26)11-19(16)36-23/h3-11,34H,12H2,1-2H3,(H2,30,31,32,35)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
12 -10.8n/an/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...


US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair