BindingDB logo
myBDB logout

BDBM260890 US9540323, 81::US9540323, example 81

SMILES: CCOC(=O)c1ccc(O)c2N(CC(C)(C)c12)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=OENYXEPFSVSFPQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260890   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y1


(Homo sapiens (Human))
BDBM260890
PNG
(US9540323, 81 | US9540323, example 81)
Show SMILES CCOC(=O)c1ccc(O)c2N(CC(C)(C)c12)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C27H26F3N3O5/c1-4-37-24(35)18-13-14-21(34)23-22(18)26(2,3)15-33(23)20-8-6-5-7-19(20)32-25(36)31-16-9-11-17(12-10-16)38-27(28,29)30/h5-14,34H,4,15H2,1-3H3,(H2,31,32,36)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
8.60 -11.0n/an/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...


US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair