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BDBM261833 2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-methyl-N-(methylsulphonyl)-1H-benzimidazole-5-carboxamide::US9708311, 84

SMILES: CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)N(C)S(C)(=O)=O

InChI Key: InChIKey=ABXWYZRPBQPAAG-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261833   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM261833
PNG
(2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...)
Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)N(C)S(C)(=O)=O
Show InChI InChI=1S/C27H28N4O4S/c1-5-30-23-9-7-6-8-20(23)21-16-18(10-12-24(21)30)26-28-22-17-19(27(32)29(2)36(4,33)34)11-13-25(22)31(26)14-15-35-3/h6-13,16-17H,5,14-15H2,1-4H3
PDB

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PC cid
PC sid
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US Patent
n/an/a 143n/an/an/an/an/a25



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...


US Patent US9708311 (2017)


BindingDB Entry DOI: 10.7270/Q23F4RPM
More data for this
Ligand-Target Pair