BDBM26194 4-Hydroxybenzoate, III::4-hydroxybenzoic acid::CHEMBL441343::p-Hydroxybenzoic acid::phenol derivative, 8
SMILES OC(=O)c1ccc(O)cc1
InChI Key InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 39 hits for monomerid = 26194
Affinity DataKi: 870nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 920nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.67E+3nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.73E+3nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.08E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 5.70E+3nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.16E+3nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.27E+3nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.61E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.13E+3nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.78E+3nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.79E+3nMAssay Description:Inhibition of mouse CA13 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.46E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 9.32E+3nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nM ΔG°: -6.83kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nM ΔG°: -6.78kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.14E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 3.43E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8.60E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.18E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 6.75E+5nM ΔG°: -4.32kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
Affinity DataKi: 6.96E+5nM ΔG°: -4.30kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 7.16E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8.09E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+6nM ΔG°: -4.05kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
TargetSuccinate-semialdehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against SSADHMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
Affinity DataIC50: 9.35E+3nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+5nMAssay Description:Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...More data for this Ligand-Target Pair
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against GABATMore data for this Ligand-Target Pair
Affinity DataIC50: 7.24E+4nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Positive allosteric modulation of human D1R expressed in HEK293 cells assessed as increase in dopamine-induced cAMP accumulation after 60 mins by HTR...More data for this Ligand-Target Pair