BDBM2624 1-methyl-3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indole-6-carboxamide::Bisindolylmaleimide deriv. 46::ROCHE screening, 47

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)C(N)=O)c2ccccc12

InChI Key InChIKey=JDFHTCHKNZWWME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2624   

TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University Of Dortmund

LigandPNGBDBM2624(1-methyl-3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2...)
Affinity DataIC50:  2.24E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
Roche Products

LigandPNGBDBM2624(1-methyl-3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2...)
Affinity DataIC50:  9.50E+3nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed