BDBM264252 6-(2,6-Dichlorophenyl)-2-((3-methyl-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 7

SMILES Cc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCNCC1

InChI Key InChIKey=YEJTUDQTVDHJEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264252   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264252(6-(2,6-Dichlorophenyl)-2-((3-methyl-4-(piperazin-1...)
Affinity DataIC50:  105nMAssay Description:Compounds were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWee1-like protein kinase(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264252(6-(2,6-Dichlorophenyl)-2-((3-methyl-4-(piperazin-1...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent