BDBM2645 (Phenylindolyl)maleimide deriv. 67::3-(3-methoxyphenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES COc1cccc(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12

InChI Key InChIKey=NQCRLEIXYKDVLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2645   

TargetProtein kinase C beta type(Rattus norvegicus (rat))
Roche Products

LigandPNGBDBM2645((Phenylindolyl)maleimide deriv. 67 | 3-(3-methoxyp...)
Affinity DataIC50:  8.00E+3nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2645((Phenylindolyl)maleimide deriv. 67 | 3-(3-methoxyp...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2645((Phenylindolyl)maleimide deriv. 67 | 3-(3-methoxyp...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed