BDBM2651 (Phenylindolyl)maleimide deriv. 73::3-(2-chlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2ccccc2Cl)c2ccccc12

InChI Key InChIKey=OMZWEMXAKFVJGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2651   

TargetProtein kinase C beta type(Rattus norvegicus (rat))
Roche Products

LigandPNGBDBM2651((Phenylindolyl)maleimide deriv. 73 | 3-(2-chloroph...)
Affinity DataIC50:  900nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2651((Phenylindolyl)maleimide deriv. 73 | 3-(2-chloroph...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2651((Phenylindolyl)maleimide deriv. 73 | 3-(2-chloroph...)
Affinity DataIC50:  760nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed