BDBM26524 (1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 1
SMILES NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)c(F)c2)C[C@@H]1C(=O)NO
InChI Key InChIKey=ZVRPHGZPZLMEPV-PIKZIKFNSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 26524
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.140nM ΔG°: -13.3kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
Affinity DataKi: <1.40E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.07E+6nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair