BDBM269090 2,5-Dichloro-N-[2-methoxy-4-(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-phenyl]-benzenesulfonamide::US9718825, Example 534

SMILES COc1cc(ccc1NS(=O)(=O)c1cc(Cl)ccc1Cl)-c1ncc2c(C)n[nH]c2n1

InChI Key InChIKey=ZAJPJFWZMSCXHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269090   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM269090(2,5-Dichloro-N-[2-methoxy-4-(3-methyl-1H-pyrazolo[...)
Affinity DataIC50: <1.5nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent