BDBM269259 US10071086, Compound 7

SMILES CN(C)c1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccc(F)c3)c2c1

InChI Key InChIKey=VXFNADKSHARJGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269259   

TargetBeta-catenin-interacting protein 1(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269259(US10071086, Compound 7)
Affinity DataIC50:  1.90E+3nMAssay Description:Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269259(US10071086, Compound 7)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent