BDBM26996 CHEMBL21485::PhB(OH)2::Phenyl-boronic acid::Phenylboronic acid, 22::benzeneboronic acid::phenylboranediol::phenylboronic acid

SMILES OB(O)c1ccccc1

InChI Key InChIKey=HXITXNWTGFUOAU-UHFFFAOYSA-N

Data  95 KI  4 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 99 hits for monomerid = 26996   

TargetChymotrypsinogen A(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  200nMAssay Description:Inhibition constant of the compound was determined against ChymotrypsinogenMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  880nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  880nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  880nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universit£ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  7.00E+3nM ΔG°:  -6.91kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Florida

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.00E+3nMpH: 8.3Assay Description:Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.10E+3nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Astrosclera willeyana)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.05E+4nMAssay Description:Inhibitory activity against E. coli AmpC beta-lactamase.More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA13 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 15(Mus musculus)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of mouse CA15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetSuccinyl-diaminopimelate desuccinylase(Haemophilus influenzae)
Loyola University

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  5.69E+4nMAssay Description:Inhibition of Haemophilus influenzae recombinant DapE by competitive binding assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Universita degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  6.78E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Helicobacter pylori)
UniversitÓ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  7.30E+4nM ΔG°:  -5.64kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
TargetGamma carbonic anhydrase family protein(Vibrio cholerae)
Universit£ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.10E+4nM ΔG°:  -5.48kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae)
Universit£ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.50E+4nM ΔG°:  -5.46kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  9.20E+4nMAssay Description:Inhibition of human recombinant full length CA14More data for this Ligand-Target Pair
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  9.60E+4nMAssay Description:Competitive inhibition of Subtilisin BL wild type enzyme from B. lentusMore data for this Ligand-Target Pair
TargetAlpha-carbonic anhydrase(Helicobacter pylori (strain G27))
Universit£ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  9.70E+4nM ΔG°:  -5.38kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetAlpha-carbonic anhydrase(Helicobacter pylori)
UniversitÓ degli Studi di Firenze

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  9.70E+4nM ΔG°:  -5.47kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
TargetSubtilisin Carlsberg(Bacillus licheniformis)
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.00E+5nMAssay Description:Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentusMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human carbonic anhydrase-1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Candida glabrata)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of Candida glabrata carbonic anhydrase by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human recombinant catalytic domain CA9More data for this Ligand-Target Pair
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.41E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.55E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  2.00E+5nMAssay Description:Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab)More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  2.30E+5nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  4.70E+5nMAssay Description:Compound was tested for the inhibition of subtilisinMore data for this Ligand-Target Pair
TargetBeta-lactamase TEM(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  4.91E+5nMAssay Description:Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coliMore data for this Ligand-Target Pair
TargetChymotrypsinogen A(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  6.40E+5nMAssay Description:Compound was tested for the inhibition of chymotrypsinMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.00E+5nMAssay Description:Inhibition of human recombinant catalytic domain CA12More data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.20E+5nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  8.20E+5nMAssay Description:Inhibition of human secreted carbonic anhydrase 4 measured by CO2 hydration reaction assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.05E+6nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  1.56E+6nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetUrease(Glycine max (Soybean))
Banaras Hindu University

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Show SMILES OB(O)c1ccccc1
Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
Affinity DataKi:  2.00E+6nM ΔG°:  -3.83kcal/molepH: 7.0 T: 2°CAssay Description:The inhibition studies of soybean urease were initiated with boric acid and boronic acids (butylboronic acid, 4-bromophenylboronic acid, and phenylbo...More data for this Ligand-Target Pair
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