BDBM270510 (R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-quinolin-1-yl)methyl)amino)isonicotinic acid::US10059687, Example 9A::US11001568, Example 9A::US11731954, Example 9A and 9B

SMILES CCc1ccccc1-c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1

InChI Key InChIKey=DPXUPGGXVOBSKO-QHCPKHFHSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 270510   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50: <100nMAssay Description:Jarid1b: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270510((R)-3-(((6-(2-ethylphenyl)-1,2,3,4-tetrahydroiso-q...)
Affinity DataIC50:  5.50E+3nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent