BDBM270533 (S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)isoindolin-1-yl)methyl)amino)isonicotinic acid::US10059687, Example 20B::US11001568, Example 20B

SMILES CCCc1ccc(cc1)N(C)c1ccc2[C@@H](CNc3cnccc3C(O)=O)N(C)Cc2c1

InChI Key InChIKey=FVXXFMCNHUPXTQ-RUZDIDTESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 270533   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50:  5.50E+3nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50: <100nMAssay Description:Jarid1b: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50:  550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50:  5.50E+3nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270533((S)-3-(((2-methyl-5-(methyl(4-propylphenyl)amino)i...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent