BDBM270585 (S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromethyl) cyclopropyl)-1H- 1,2,3-triazol-4- yl)methyl)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-17::US10577352, Compound I-17

SMILES CC(C)(C)CNc1ncnc2c(cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12)C#N

InChI Key InChIKey=DXFKFNWGYXPFEX-QHCPKHFHSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 270585   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270585((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...)
Affinity DataIC50:  3.30nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270585((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...)
Affinity DataEC50:  59nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270585((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...)
Affinity DataIC50:  3.30nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270585((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...)
Affinity DataEC50:  59nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent