BDBM271379 US10064861, Compound 33
SMILES COc1ccc2n3CCn4cc(cn4)-c4ccc(=O)n(Cc5cccc(c5)C(=O)Nc3nc2c1)n4
InChI Key InChIKey=BCWOQAIKLLZJQT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 271379
Affinity DataIC50: <100nMpH: 7.0Assay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712) IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMpH: 7.0Assay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)) In this assay, IRAK-1 hydrolyses ATP and autophosphorylates.Measurement of IRA...More data for this Ligand-Target Pair