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BDBM275066 US10221195, Example 8::US9879032, Example 8

SMILES: COc1ccc(CN2CCOc3ncc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3C2=O)c(CO)c1

InChI Key: InChIKey=WTXBDFUIXOEUOR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275066   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM275066
PNG
(US10221195, Example 8 | US9879032, Example 8)
Show SMILES COc1ccc(CN2CCOc3ncc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3C2=O)c(CO)c1
Show InChI InChI=1S/C24H24ClN3O7S/c1-33-19-5-3-15(16(9-19)14-29)13-28-7-8-35-23-20(24(28)30)11-18(12-26-23)27-36(31,32)22-10-17(25)4-6-21(22)34-2/h3-6,9-12,27,29H,7-8,13-14H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 9.10n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...


US Patent US10221195 (2019)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q2QZ2D83
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM275066
PNG
(US10221195, Example 8 | US9879032, Example 8)
Show SMILES COc1ccc(CN2CCOc3ncc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3C2=O)c(CO)c1
Show InChI InChI=1S/C24H24ClN3O7S/c1-33-19-5-3-15(16(9-19)14-29)13-28-7-8-35-23-20(24(28)30)11-18(12-26-23)27-36(31,32)22-10-17(25)4-6-21(22)34-2/h3-6,9-12,27,29H,7-8,13-14H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 9.10n/an/an/an/an/a25



Daiichi Sankyo Company, Limited

US Patent


Assay Description
COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In...


US Patent US9879032 (2018)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q2F76FKB
More data for this
Ligand-Target Pair