BDBM276754 N-(1,1-dioxidotetrahydro- thiophen-3-yl)-2-(5-((3- ethoxypyridin-2-yl)oxy) pyridin-3-yl)pyrimidine- 5-carboxamide::US10071992, Example 3.3::US11034678, Example 3.3::US11065249, WO2018033832-Ex.-3.3::WO2018033832, Ex. 3.3
SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1CCS(=O)(=O)C1
InChI Key InChIKey=YCVMSJOECUPLAC-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 276754
Affinity DataIC50: 196nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 insect cell membrane using [1-14C]decanoyl-CoA and 1,2-didecanoyl-sn-glycerol as substrates assessed as in...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair