BDBM279457 (R)-1-(5-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-1H-benzo[d]imidazol-2-yl)-3-methylbutan-1-amine::US10035777, Example 8
SMILES CC(C)C[C@@H](N)c1nc2cc(ccc2[nH]1)-c1ncnc2[nH]ccc12
InChI Key InChIKey=VZHOFNCZZAQEPS-KWWJGWKXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 279457
Affinity DataIC50: 4nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair