BDBM280476 US10030020, Example 21::US10781211, Example 21

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3ccc(Cl)cc3N3CCOCC3)C2)CC1)C(F)(F)F

InChI Key InChIKey=WHKLAKOMDYXEPV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 280476   

TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50: >1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50:  550nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50: <100nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50: >1.00E+3nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD2(Mus musculus (Mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280476(US10030020, Example 21 | US10781211, Example 21)
Affinity DataIC50:  550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent