BDBM283452 N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((3-chloroquinolin-6-yl)methyl)-6- methylisonicotinamide::US10023557, Example 104::US10023557, Example 197::US10266515, Example 104::US10308637, Example 197::US11021463, Example 104::US9611252, Example 104
SMILES Cc1cc(cc(Cc2ccc3ncc(Cl)cc3c2)n1)C(=O)NCc1c(C)cc(N)nc1C
InChI Key InChIKey=WDMJJASBQUYWJX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 283452
Affinity DataIC50: <100nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:The test compounds at various concentrations, also prepared by serial dilutions as described above, are added to the test wells. The volume of test c...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:The test compounds at various concentrations, also prepared by serial dilutions as described above, are added to the test wells. The volume of test c...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Lifesci Pharmaceuticals
US Patent
Lifesci Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Lifesci Pharmaceuticals
US Patent
Lifesci Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair