BDBM28579 1-sulfonylindazole, 7a::N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]piperidine-4-carboxamide

SMILES O=C(Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12)C1CCNCC1

InChI Key InChIKey=KVDHEMNUTADYJJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 28579   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  2.30nM ΔG°:  -11.7kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  130nM ΔG°:  -9.29kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  6.90E+3nM ΔG°:  -6.97kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  8.50E+3nM ΔG°:  -6.84kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed