BDBM285865 US10081606, Compound I-14::US9765038, Compound I-14

SMILES COc1cccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC

InChI Key InChIKey=GZIGQTZRHLRBJL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 285865   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM285865(US10081606, Compound I-14 | US9765038, Compound I-...)
Affinity DataIC50:  650nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-249,301-1210,T790M,L858R](Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM285865(US10081606, Compound I-14 | US9765038, Compound I-...)
Affinity DataIC50:  5.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM285865(US10081606, Compound I-14 | US9765038, Compound I-...)
Affinity DataIC50:  650nMAssay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM285865(US10081606, Compound I-14 | US9765038, Compound I-...)
Affinity DataIC50:  5.5nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent