BDBM286221 6-fluoro-3-methyl-2-(5- methoxypyridin-3- yl)imidazo[1,2-a]pyridine::US9518055, Example 18

SMILES COc1cncc(c1)-c1nc2ccc(F)cn2c1C

InChI Key InChIKey=SZBAIFHYRBMLFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286221   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286221(6-fluoro-3-methyl-2-(5- methoxypyridin-3- yl)imida...)
Affinity DataIC50:  32.4nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286221(6-fluoro-3-methyl-2-(5- methoxypyridin-3- yl)imida...)
Affinity DataIC50:  0.300nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent