BDBM28960 (2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlorobenzene)sulfonamido}propyl N-propylcarbamate::BMCL18464 Compound 14::CHEMBL181204::phenylsulfonamide, 1a
SMILES CCCNC(=O)OC[C@@H](C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=YPEBFRLSFJTTLH-CQSZACIVSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 28960
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 85nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 10nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair