BDBM292281 US10100057, Example 136::US11046702, Example 136::US9745310, Example 136

SMILES COc1cc(ccc1-c1cnc2nc(COc3ccccn3)cn2c1)C#N

InChI Key InChIKey=FCAGGHXOJNRJQE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292281   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292281(US10100057, Example 136 | US11046702, Example 136 ...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292281(US10100057, Example 136 | US11046702, Example 136 ...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292281(US10100057, Example 136 | US11046702, Example 136 ...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent