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BDBM292789 US10106501, Example EH-1

SMILES: Cc1cn(C(=O)c2c(Cl)ccc(C(=O)N3CCC(CC3)C(O)=O)c2Cl)c2c(C)cc(OC(F)(F)F)cc12

InChI Key: InChIKey=ONYFLSUKTFIHND-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292789   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM292789
PNG
(US10106501, Example EH-1)
Show SMILES Cc1cn(C(=O)c2c(Cl)ccc(C(=O)N3CCC(CC3)C(O)=O)c2Cl)c2c(C)cc(OC(F)(F)F)cc12
Show InChI InChI=1S/C25H21Cl2F3N2O5/c1-12-9-15(37-25(28,29)30)10-17-13(2)11-32(21(12)17)23(34)19-18(26)4-3-16(20(19)27)22(33)31-7-5-14(6-8-31)24(35)36/h3-4,9-11,14H,5-8H2,1-2H3,(H,35,36)
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PC cid
PC sid
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US Patent
n/an/a 300n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair