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BDBM292826 US10106501, Example FE

SMILES: Cn1c(Cc2c(Cl)ccc(C(=O)N3CCC(CC(O)=O)CC3)c2Cl)cc2c(F)cc(cc12)C(F)(F)F

InChI Key: InChIKey=KLGFFKGIDCNTCD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292826   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM292826
PNG
(US10106501, Example FE)
Show SMILES Cn1c(Cc2c(Cl)ccc(C(=O)N3CCC(CC(O)=O)CC3)c2Cl)cc2c(F)cc(cc12)C(F)(F)F
Show InChI InChI=1S/C25H22Cl2F4N2O3/c1-32-15(12-18-20(28)9-14(10-21(18)32)25(29,30)31)11-17-19(26)3-2-16(23(17)27)24(36)33-6-4-13(5-7-33)8-22(34)35/h2-3,9-10,12-13H,4-8,11H2,1H3,(H,34,35)
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US Patent
n/an/a<100n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair