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BDBM292849 US10106501, Example FT

SMILES: COCCC1CCN(CC1)C(=O)c1ccc(Cl)c(Cc2cc3c(C)cc(nc3n2C)C(F)(F)F)c1Cl

InChI Key: InChIKey=NJEBCAKTQLXBCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292849   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM292849
PNG
(US10106501, Example FT)
Show SMILES COCCC1CCN(CC1)C(=O)c1ccc(Cl)c(Cc2cc3c(C)cc(nc3n2C)C(F)(F)F)c1Cl
Show InChI InChI=1S/C26H28Cl2F3N3O2/c1-15-12-22(26(29,30)31)32-24-19(15)13-17(33(24)2)14-20-21(27)5-4-18(23(20)28)25(35)34-9-6-16(7-10-34)8-11-36-3/h4-5,12-13,16H,6-11,14H2,1-3H3
PDB

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PC cid
PC sid
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US Patent
n/an/a<100n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair