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BDBM292854 US10106501, Example FY

SMILES: COCCC1CCN(CC1)C(=O)c1ccc(Cl)c(C(=O)c2cc3c(C)cc(nc3n2C)C(F)(F)F)c1Cl

InChI Key: InChIKey=PEOOGPKLIIUWDL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292854   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM292854
PNG
(US10106501, Example FY)
Show SMILES COCCC1CCN(CC1)C(=O)c1ccc(Cl)c(C(=O)c2cc3c(C)cc(nc3n2C)C(F)(F)F)c1Cl
Show InChI InChI=1S/C26H26Cl2F3N3O3/c1-14-12-20(26(29,30)31)32-24-17(14)13-19(33(24)2)23(35)21-18(27)5-4-16(22(21)28)25(36)34-9-6-15(7-10-34)8-11-37-3/h4-5,12-13,15H,6-11H2,1-3H3
PDB

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PC cid
PC sid
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US Patent
n/an/a 300n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair