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BDBM293096 US10106501, Example BC

SMILES: Cc1ncc(C(=O)N2CCC(CC(O)=O)CC2)c(C)c1Cc1cc2c(C)cc(cc2n1C)C(F)(F)F

InChI Key: InChIKey=RSPHZVYRXMNQLW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293096   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM293096
PNG
(US10106501, Example BC)
Show SMILES Cc1ncc(C(=O)N2CCC(CC(O)=O)CC2)c(C)c1Cc1cc2c(C)cc(cc2n1C)C(F)(F)F
Show InChI InChI=1S/C27H30F3N3O3/c1-15-9-19(27(28,29)30)11-24-21(15)12-20(32(24)4)13-22-16(2)23(14-31-17(22)3)26(36)33-7-5-18(6-8-33)10-25(34)35/h9,11-12,14,18H,5-8,10,13H2,1-4H3,(H,34,35)
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PC cid
PC sid
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US Patent
n/an/a 300n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair