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BDBM293125 US10106501, Example BJ-17

SMILES: Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(C(=O)N4CCC(CC4)C4COC4)c3Cl)nc12)C(F)(F)F

InChI Key: InChIKey=XOMKPRVKZPSGCT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM293125
PNG
(US10106501, Example BJ-17)
Show SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(C(=O)N4CCC(CC4)C4COC4)c3Cl)nc12)C(F)(F)F
Show InChI InChI=1S/C26H26Cl2F3N3O2/c1-14-9-17(26(29,30)31)10-21-24(14)32-22(33(21)2)11-19-20(27)4-3-18(23(19)28)25(35)34-7-5-15(6-8-34)16-12-36-13-16/h3-4,9-10,15-16H,5-8,11-13H2,1-2H3
PDB

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PC cid
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US Patent
n/an/a<100n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair