BDBM29315 2-amino-1,3,4-thiadiazole, 9

SMILES Nc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1

InChI Key InChIKey=NQQBNZBOOHHVQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29315   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29315(2-amino-1,3,4-thiadiazole, 9)
Affinity DataIC50:  239nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM29315(2-amino-1,3,4-thiadiazole, 9)
Affinity DataIC50:  700nMAssay Description:Inhibition of JNK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29315(2-amino-1,3,4-thiadiazole, 9)
Affinity DataIC50:  700nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed