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BDBM293193 US10106501, Example BW-15

SMILES: Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(CN4CCN(CC(F)(F)F)CC4)c3Cl)nc12)C(F)(F)F

InChI Key: InChIKey=GLXROVPBTIMOCP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293193   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM293193
PNG
(US10106501, Example BW-15)
Show SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(CN4CCN(CC(F)(F)F)CC4)c3Cl)nc12)C(F)(F)F
Show InChI InChI=1S/C24H24Cl2F6N4/c1-14-9-16(24(30,31)32)10-19-22(14)33-20(34(19)2)11-17-18(25)4-3-15(21(17)26)12-35-5-7-36(8-6-35)13-23(27,28)29/h3-4,9-10H,5-8,11-13H2,1-2H3
PDB

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PC cid
PC sid
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US Patent
n/an/a 300n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...


US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair